Sunday, December 10, 2017
This site was created to collect new evidence-based studies on medical topics. It is our hope and intention that this will serve as a helpful tool for physicians, health practitioners, and patients who want to keep up to date with current trends in medical studies and technology.
The contents of the Medical Health Discoveries web site such as images, graphics, and text ("Content") are for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because you have read something on the Internet.
Monday, November 12, 2012
Thursday, August 18, 2011
U.S. researchers have made an amazing breakthrough in cancer research. They have modified patients' immune systems to attack cancer cells of the blood (leukemia). Modified T-cells are turned into serial killers and are genetically programmed to attack cancer cells. Three chronic lymphocytic leukemia (CLL) patients with no hope to live and all options run out, participated in this study at the University of Pennsylvania where researchers engineered their T lymphocytes to attack cancerous B cells.
Carl June, a professor of pathology and laboratory medicine at the school’s Abramson Cancer Center, was the main lead author. “The actual trial exceeded our wildest outcome and imagination actually," says Carl June, professor of pathology and laboratory medicine, who was the study’s lead author, "because what we found is all three patients have had a remarkable anti-tumor response and that literally pounds of leukemia have been eradicated in all three patients.”
Two of the three CLL patients had a complete remission of their disease and there was a significant improvement in the third.
The T cells were genetically modified using a harmless virus, which carried an anti-body called a chimeric antigen receptor (CAR). The CAR was binded to another protein called CD19 that’s present on the surface of normal B lymphocytes and all CLL tumor cells.
Michael Kalos, one of the researchers, also mentioned that they bound a signaling molecule that binds to CD19 that would continue production of thousands of T cells that would act against future cancerous B cells should it return.
“We saw a substantial number of cells remaining circulating and in the marrow of patients very, very late after infusion, nine to 12 months, entirely unprecedented in the field," says Kalos. "And finally we saw that those cells, not only did they remain there, but they were able to be triggered, recognize and kill cancer cells when they encountered them again.”
The study can be found in the New England Journal of Medicine.
Friday, February 18, 2011
A team of researchers from UCLA and the Veterans Administration were investigating the effects of stress on gastrointestinal functions. They were using mice that overproduced a stress hormone called corticotrophin-releasing factor (CRF). The stress hormone caused them to lose their hair as they got older.
Researchers studied the effects of CRF on the colon. They also wanted to study what would happen to the intestines if the stress hormone was removed. They injected a peptide called Astressin-B over five days.
They moved the bald mice back to a cage with their hairy siblings, and when they came back three months later -- they could no longer visually identify their original set of bald mice. All of them grew hair!
Subsequent studies have shown that Astressin-B can not only regrow hair but can also prevent hair loss with younger mice that overproduced the stress hormone.
The study is now published in peer review journal called PLoS One.
Wednesday, February 16, 2011
Sunday, January 16, 2011
The long term effects of smoking has been well known over the past few years as documented cases of heart disease and cancer has been well reviewed. But new research published in Chemical Research in Toxicology has identified potentially harmful effects immediately your first cigarette of the day.
Researchers looked at a specific level of chemicals called polycyclic aromatic hydrocarbons (PAH) in 12 patients after they smoked. The results show that PAH immediately was processed in the body and it converted into another chemical to damage DNA, which is known to be the primary cause of cancer. This horrifying effect took only 15 to 30 minutes.
Wednesday, November 10, 2010
White rice increases the chances of type 2 diabetes, according to Harvard researchers. Their study published in the Archives of Internal Medicine covered nearly 200,000 people which showed anyone that ate more than 5 servings of white rice per week had a 17% higher risk of diabetes compared with those that ate less than 1 serving of white rice a month.
In contrast, high brown rice intake was associated with a lower risk of type 2 diabetes.
The study suggests that eating whole grains such as brown rice instead of white rice may lower risk of type 2 diabetes and that most of our carbohydrate intake should come from whole grains rather than refined grains.